2 years ago

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In the recent research we analyzed a panel of human melanoma cell lines with defined oncogenic alterations for sensitivity to PL 4032. Additionally, with Alisertib read more...



2 years ago

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According to TCGA information, down regulated ABCB1 predicted greater survival of GBM sufferers. Com bining a statin that has a chemotherapeutic agent represents a highly effective, likely strategy for circumventing resist ance and drastically enh read more...



2 years ago

Sick Of All The KU55933PI-103Alisertib Gossip? I Am Here On Your Behalf

The resistant M233 cell line has a homozygous PTEN deletion and has no PTEN protein by Western blot. This corre lates with baseline pAkt detectable in M233 but not M229, at the same time as increase in pAkt on PL 4032 e po absolutely sure within t read more...